MUC1 positive cutaneous metastasis with transepidermal elimination from a breast carcinoma

• Main Authors: Luna A, Merino ME, Alberdi CG, Abba MC, Segal-Eiras A, Croce MV
• Format: Article
• Language: English
• Published: Dove Medical Press 2013-11-01
• Series: International Medical Case Reports Journal
• Online Access: http://www.dovepress.com/muc1-positive-cutaneous-metastasis-with-transepidermal-elimination-fro-a14930

Amalia Luna, Maria Emilia Merino, Cecilio G Alberdi, Martin C Abba, Amada Segal-Eiras, Maria Virginia Croce Center of Basic and Applied Immunological Research, Faculty of Medical Sciences, National University of La Plata, Argentina Abstract: Breast cancer is the most common cause of cutaneous metastases from internal malignancies. Generally, the neoplastic cells are located in the dermis or hypodermis, while a finding of transepidermal elimination on cutaneous metastases is exceptional. In this report we present a patient with perforating cutaneous metastases from breast cancer with mucin 1 expression. Cutaneous, bone, lung, and hepatic lesions were detected two years after the diagnosis of the primary tumor. Keywords: breast cancer, cutaneous metastasis, transepidermal elimination, MUC1