Macrophage receptors responsible for distinct recognition of low density lipoprotein containing pyrrole or pyridinium adducts: models of oxidized low density lipoprotein

Macrophage receptors responsible for distinct recognition of low density lipoprotein containing pyrrole or pyridinium adducts: models of oxidized low density lipoprotein

Oxidation of low density lipoproteins (LDL) induced by incubation with Cu2+ ions results in the formation of a heterogeneous group of aldehydic adducts on lysyl residues (Lys) of apolipoprotein B (apoB) that are thought to be responsible for the uptake of oxidized LDL (oxLDL) by macrophages. To defi...

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Bibliographic Details
Main Authors: Eugene A. Podrez, George Hoppe, June O'Neil, Lawrence M. Sayre, Nader Sheibani, Henry F. Hoff
Format: Article
Language:English
Published: Elsevier 2000-09-01
Series:Journal of Lipid Research
Subjects:
oxidized LDL
scavenger receptor class A
SR-A
CD36
mouse peritoneal macrophages
2,5-hexanedione-modified LDL
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520334581

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