Choriodecidual infection downregulates angiogenesis and morphogenesis pathways in fetal lungs from Macaca nemestrina.

Choriodecidual infection downregulates angiogenesis and morphogenesis pathways in fetal lungs from Macaca nemestrina.

Intrauterine exposure to amniotic fluid (AF) cytokines is thought to predispose to bronchopulmonary dysplasia (BPD). We evaluated the effects of GBS exposure on RNA expression in fetal lung tissue to determine early molecular pathways associated with fetal lung injury that may progress to BPD.Ten ch...

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Bibliographic Details
Main Authors: Ryan M McAdams, Jeroen Vanderhoeven, Richard P Beyer, Theo K Bammler, Federico M Farin, H Denny Liggitt, Raj P Kapur, Michael G Gravett, Craig E Rubens, Kristina M Adams Waldorf
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3467273?pdf=render

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