The degeneration and replacement of dopamine cells in Parkinson’s disease: the role of aging.

The degeneration and replacement of dopamine cells in Parkinson’s disease: the role of aging.

Available data show marked similarities for the degeneration of dopamine cells in Parkinson’s disease and aging. The etio-pathogenic agents involved are very similar in both cases, and include free radicals, different mitochondrial disturbances, alterations of the mitophagy and the ubiquitin-proteas...

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Bibliographic Details
Main Authors: Manuel eRodriguez, Ingrid eMorales, Clara eRodriguez-Sabate, Alberto eSanchez, Rafael eCastro, Jose Miguel eBrito, Magdalena eSabate
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-08-01
Series:Frontiers in Neuroanatomy
Subjects:
Aging
Dopamine
Parkinson’s disease
nigrostriatal cells
etiopathology.
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnana.2014.00080/full

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