Use of Aleuria alantia Lectin Affinity Chromatography to Enrich Candidate Biomarkers from the Urine of Patients with Bladder Cancer

Use of Aleuria alantia Lectin Affinity Chromatography to Enrich Candidate Biomarkers from the Urine of Patients with Bladder Cancer

Developing a urine test to detect bladder tumours with high sensitivity and specificity is a key goal in bladder cancer research. We hypothesised that bladder cancer-specific glycoproteins might fulfill this role. Lectin-ELISAs were used to study the binding of 25 lectins to 10 bladder cell lines a...

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Bibliographic Details
Main Authors: Sarah R. Ambrose, Naheema S. Gordon, James C. Goldsmith, Wenbin Wei, Maurice P. Zeegers, Nicholas D. James, Margaret A. Knowles, Richard T. Bryan, Douglas G. Ward
Format: Article
Language:English
Published: MDPI AG 2015-09-01
Series:Proteomes
Subjects:
bladder cancer
urine
biomarker
lectin
glycoproteome
Online Access:http://www.mdpi.com/2227-7382/3/3/266

Internet

http://www.mdpi.com/2227-7382/3/3/266

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