High throughput sequencing and proteomics to identify immunogenic proteins of a new pathogen: the dirty genome approach.
BACKGROUND:With the availability of new generation sequencing technologies, bacterial genome projects have undergone a major boost. Still, chromosome completion needs a costly and time-consuming gap closure, especially when containing highly repetitive elements. However, incomplete genome data may b...
Main Authors: | Gilbert Greub, Carole Kebbi-Beghdadi, Claire Bertelli, François Collyn, Beat M Riederer, Camille Yersin, Antony Croxatto, Didier Raoult |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2009-12-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC2793016?pdf=render |
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