A case of pulmonary tumor thrombotic microangiopathy associated with lung cancer diagnosed by cell-block immunohistochemistry of pulmonary microvascular cytology
Pulmonary tumor thrombotic microangiopathy (PTTM) is rare but should be considered as a possible diagnosis in patients with cancer. In this case, PTTM induced by lung cancer was more accurately diagnosed using cell block immunohistochemistry of pulmonary microvascular cytology (PMC) because we could...
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2019-01-01
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| Series: | Respiratory Medicine Case Reports |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2213007119301741 |
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doaj-291822b662b84166bc96b685820906fc2020-11-25T01:14:45ZengElsevierRespiratory Medicine Case Reports2213-00712019-01-0128A case of pulmonary tumor thrombotic microangiopathy associated with lung cancer diagnosed by cell-block immunohistochemistry of pulmonary microvascular cytologyHideaki Yamakawa0Tomohiro Oba1Hiroki Ohta2Yuta Tsukahara3Gen Kida4Emiri Tsumiyama5Tomotaka Nishizawa6Rie Kawabe7Shintaro Sato8Keiichi Akasaka9Masako Amano10Kazuyoshi Kuwano11Hidekazu Matsushima12Department of Respiratory Medicine, Saitama Red Cross Hospital, Saitama, Japan; Department of Respiratory Medicine, Tokyo Jikei University Hospital, Tokyo, Japan; Corresponding author. Department of Respiratory Medicine, Saitama Red Cross Hospital, 1-5 Shintoshin, Chuo-ku, Saitama, 330-8553, Japan.Department of Respiratory Medicine, Saitama Red Cross Hospital, Saitama, JapanDepartment of Respiratory Medicine, Saitama Red Cross Hospital, Saitama, JapanDepartment of Respiratory Medicine, Saitama Red Cross Hospital, Saitama, JapanDepartment of Respiratory Medicine, Saitama Red Cross Hospital, Saitama, JapanDepartment of Respiratory Medicine, Saitama Red Cross Hospital, Saitama, Japan; Department of Respiratory Medicine, Tokyo Jikei University Hospital, Tokyo, JapanDepartment of Respiratory Medicine, Saitama Red Cross Hospital, Saitama, JapanDepartment of Respiratory Medicine, Saitama Red Cross Hospital, Saitama, JapanDepartment of Respiratory Medicine, Saitama Red Cross Hospital, Saitama, JapanDepartment of Respiratory Medicine, Saitama Red Cross Hospital, Saitama, JapanDepartment of Respiratory Medicine, Saitama Red Cross Hospital, Saitama, JapanDepartment of Respiratory Medicine, Tokyo Jikei University Hospital, Tokyo, JapanDepartment of Respiratory Medicine, Saitama Red Cross Hospital, Saitama, JapanPulmonary tumor thrombotic microangiopathy (PTTM) is rare but should be considered as a possible diagnosis in patients with cancer. In this case, PTTM induced by lung cancer was more accurately diagnosed using cell block immunohistochemistry of pulmonary microvascular cytology (PMC) because we could confirm that lung adenocarcinoma was the origin of PTTM by the positive result of TTF-1 for atypical cells in PMC. The PMC procedure was minimally invasive and safer than lung biopsy. We believe that the cell block technique of PMC should be considered as one diagnostic option in PTTM. Keywords: Pulmonary tumor thrombotic microangiopathy, Pulmonary microvascular cytology, Cell block techniquehttp://www.sciencedirect.com/science/article/pii/S2213007119301741 |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Hideaki Yamakawa Tomohiro Oba Hiroki Ohta Yuta Tsukahara Gen Kida Emiri Tsumiyama Tomotaka Nishizawa Rie Kawabe Shintaro Sato Keiichi Akasaka Masako Amano Kazuyoshi Kuwano Hidekazu Matsushima |
| spellingShingle |
Hideaki Yamakawa Tomohiro Oba Hiroki Ohta Yuta Tsukahara Gen Kida Emiri Tsumiyama Tomotaka Nishizawa Rie Kawabe Shintaro Sato Keiichi Akasaka Masako Amano Kazuyoshi Kuwano Hidekazu Matsushima A case of pulmonary tumor thrombotic microangiopathy associated with lung cancer diagnosed by cell-block immunohistochemistry of pulmonary microvascular cytology Respiratory Medicine Case Reports |
| author_facet |
Hideaki Yamakawa Tomohiro Oba Hiroki Ohta Yuta Tsukahara Gen Kida Emiri Tsumiyama Tomotaka Nishizawa Rie Kawabe Shintaro Sato Keiichi Akasaka Masako Amano Kazuyoshi Kuwano Hidekazu Matsushima |
| author_sort |
Hideaki Yamakawa |
| title |
A case of pulmonary tumor thrombotic microangiopathy associated with lung cancer diagnosed by cell-block immunohistochemistry of pulmonary microvascular cytology |
| title_short |
A case of pulmonary tumor thrombotic microangiopathy associated with lung cancer diagnosed by cell-block immunohistochemistry of pulmonary microvascular cytology |
| title_full |
A case of pulmonary tumor thrombotic microangiopathy associated with lung cancer diagnosed by cell-block immunohistochemistry of pulmonary microvascular cytology |
| title_fullStr |
A case of pulmonary tumor thrombotic microangiopathy associated with lung cancer diagnosed by cell-block immunohistochemistry of pulmonary microvascular cytology |
| title_full_unstemmed |
A case of pulmonary tumor thrombotic microangiopathy associated with lung cancer diagnosed by cell-block immunohistochemistry of pulmonary microvascular cytology |
| title_sort |
case of pulmonary tumor thrombotic microangiopathy associated with lung cancer diagnosed by cell-block immunohistochemistry of pulmonary microvascular cytology |
| publisher |
Elsevier |
| series |
Respiratory Medicine Case Reports |
| issn |
2213-0071 |
| publishDate |
2019-01-01 |
| description |
Pulmonary tumor thrombotic microangiopathy (PTTM) is rare but should be considered as a possible diagnosis in patients with cancer. In this case, PTTM induced by lung cancer was more accurately diagnosed using cell block immunohistochemistry of pulmonary microvascular cytology (PMC) because we could confirm that lung adenocarcinoma was the origin of PTTM by the positive result of TTF-1 for atypical cells in PMC. The PMC procedure was minimally invasive and safer than lung biopsy. We believe that the cell block technique of PMC should be considered as one diagnostic option in PTTM. Keywords: Pulmonary tumor thrombotic microangiopathy, Pulmonary microvascular cytology, Cell block technique |
| url |
http://www.sciencedirect.com/science/article/pii/S2213007119301741 |
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