Müller glial microRNAs are required for the maintenance of glial homeostasis and retinal architecture

Müller glia are a type of retinal glial cell important for maintaining retinal structure and implicated in response to retinal damage. Here the authors identify Brevican, a chondroitin sulfate proteoglycan, as a microRNA-modulated regulator of Müller glia function.

Bibliographic Details
Main Authors: Stefanie G. Wohl, Nikolas L. Jorstad, Edward M. Levine, Thomas A. Reh
Format: Article
Language:English
Published: Nature Publishing Group 2017-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-017-01624-y
Description
Summary:Müller glia are a type of retinal glial cell important for maintaining retinal structure and implicated in response to retinal damage. Here the authors identify Brevican, a chondroitin sulfate proteoglycan, as a microRNA-modulated regulator of Müller glia function.
ISSN:2041-1723