The Role of <i>Drosophila</i> CtIP in Homology-Directed Repair of DNA Double-Strand Breaks

DNA double-strand breaks (DSBs) are a particularly genotoxic type of DNA damage that can result in chromosomal aberrations. Thus, proper repair of DSBs is essential to maintaining genome integrity. DSBs can be repaired by non-homologous end joining (NHEJ), where ends are processed before joining thr...

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Bibliographic Details
Main Authors: Ian Yannuzzi, Margaret A. Butler, Joel Fernandez, Jeannine R. LaRocque
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Genes
Subjects:
Online Access:https://www.mdpi.com/2073-4425/12/9/1430