Intermittent Hypoxia Disrupts Glucose Homeostasis in Liver Cells in an Insulin-Dependent and Independent Manner

Intermittent Hypoxia Disrupts Glucose Homeostasis in Liver Cells in an Insulin-Dependent and Independent Manner

Background/Aims: Obstructive sleep apnea is associated with diabetes and insulin resistance, but the underlying mechanisms remain unclear. The purpose of the current study was to determine the molecular effects of intermittent hypoxia (IH) on hepatic insulin signaling and glucose homeostasis, and wh...

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Bibliographic Details
Main Authors: Chen Juan Gu, Hua Hua Yi, Jing Feng, Zhi Guo Zhang, Jun Zhou, Li Na Zhou, Jian Ping Zhou, Min Li, Qing Yun  Li
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2018-05-01
Series:Cellular Physiology and Biochemistry
Subjects:
Intermittent hypoxia
Liver cells
Glucose homeostasis
Forkhead box protein O1
C-Jun NH2-terminal-kinase
Online Access:https://www.karger.com/Article/FullText/490169

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https://www.karger.com/Article/FullText/490169

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