Dicer-Derived MicroRNAs Are Utilized by the Fragile X Mental Retardation Protein for Assembly on Target RNAs

Dicer-Derived MicroRNAs Are Utilized by the Fragile X Mental Retardation Protein for Assembly on Target RNAs

In mammalian cells, fragile X mental retardation protein (FMRP) has been reported to be part of a microRNA (miRNA)-containing effector ribonucleoprotien (RNP) complex believed to mediate translational control of specific mRNAs. Here, using recombinant proteins, we demonstrate that human FMRP can act...

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Bibliographic Details
Main Authors: Isabelle Plante, Laetitia Davidovic, Dominique L. Ouellet, Lise-Andrée Gobeil, Sandra Tremblay, Edouard W. Khandjian, Patrick Provost
Format: Article
Language:English
Published: Hindawi Limited 2006-01-01
Series:Journal of Biomedicine and Biotechnology
Online Access:http://dx.doi.org/10.1155/JBB/2006/64347

Internet

http://dx.doi.org/10.1155/JBB/2006/64347

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