IL2RA/CD25 gene polymorphisms: uneven association with multiple sclerosis (MS) and type 1 diabetes (T1D).
BACKGROUND: IL-2 receptor (IL2R) alpha is the specific component of the high affinity IL2R system involved in the immune response and in the control of autoimmunity. METHODS AND RESULTS: Here we perform a replication and fine mapping of the IL2RA gene region analyzing 3 SNPs previously associated wi...
Main Authors: | Antonio Alcina, María Fedetz, Dorothy Ndagire, Oscar Fernández, Laura Leyva, Miguel Guerrero, María M Abad-Grau, Carmen Arnal, Concepción Delgado, Miguel Lucas, Guillermo Izquierdo, Fuencisla Matesanz |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2009-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC2607550?pdf=render |
Similar Items
-
Multiple sclerosis risk variant HLA-DRB1*1501 associates with high expression of DRB1 gene in different human populations.
by: Antonio Alcina, et al.
Published: (2012-01-01) -
High ACSL5 transcript levels associate with systemic lupus erythematosus and apoptosis in Jurkat T lymphocytes and peripheral blood cells.
by: Antonio Catalá-Rabasa, et al.
Published: (2011-01-01) -
Human endogenous retrovirus HERV-Fc1 association with multiple sclerosis susceptibility: a meta-analysis.
by: Belén de la Hera, et al.
Published: (2014-01-01) -
Genome-wide association study of multiple sclerosis confirms a novel locus at 5p13.1.
by: Fuencisla Matesanz, et al.
Published: (2012-01-01) -
Fine mapping and functional analysis of the multiple sclerosis risk gene CD6.
by: Bhairavi Swaminathan, et al.
Published: (2013-01-01)