Multiparametric in vivo analyses of the brain and spine identify structural and metabolic biomarkers in men with adrenomyeloneuropathy
Objective: Progressive myelopathy causes severe handicap in men with adrenomyeloneuropathy (AMN), an X-linked disorder due to ABCD1 pathogenic variants. At present, treatments are symptomatic but disease-modifying therapies are under evaluation. Given the small effect size of clinical scales in AMN,...
Main Authors: | Isaac M. Adanyeguh, Xiaofang Lou, Eavan McGovern, Marie-Pierre Luton, Magali Barbier, Elise Yazbeck, Romain Valabregue, Dinesh Deelchand, Pierre-Gilles Henry, Fanny Mochel |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2021-01-01
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Series: | NeuroImage: Clinical |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2213158221000103 |
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