Interrelation between the system of complement, Tolllike receptors, CD antigens and cytokines in normal and pathological condition. Review

• Main Authors: M. V. Lakhtin, V. M. Lakhtin, S. S. Afanasiev, V. A. Aleshkin
• Format: Article
• Language: Russian
• Published: Scientific Сentre for Family Health and Human Reproduction Problems 2015-11-01
• Series: Acta Biomedica Scientifica
• Subjects: tlr; innate immunity; pattern recognition; complement system; toll-like receptors; cytokines; lectins; probiotics; pathogens; inflammation; probiotic bacteria
• Online Access: https://www.actabiomedica.ru/jour/article/view/141
• ISSN: 2541-9420; 2587-9596

The overview of publications of the last five years is devoted to currently described communicative relationships between complement system, antigens of CD class, Toll-like receptors, other pattern recognition receptors and recognition molecules (interleukins, other cytokines, lectins). Studied aspects of innate immunity system actions include cooperation and synergism; adaptive strategies of microbial and viral pathogens; using probiotic microorganisms; initiation, switching, amplification and termination of key pathways in host antipathogen strategies; approaches to creation of address mechanisms of treatments of diseases at the level of metabolome network communications; prospects for constructing combinative system preparations for medicine.