Therapy of Primary Hypothyroidism with α-Lipoic Acid Review of Studies Results
Primary hypothyroidism occurs in the general population with an incidence of 0.5–1 %, and includes congenital and acquired (due to autoimmune thyroiditis, after surgical removal of the thyroid gland or treatment with radioactive iodine) forms. The basic treatment of primary hypothyroidism is replace...
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Publishing House Zaslavsky
2016-05-01
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| Series: | Mìžnarodnij Endokrinologìčnij Žurnal |
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| Online Access: | http://iej.zaslavsky.com.ua/article/view/77796 |
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doaj-29dcd821325d4a0c94b3ef82ebcd3abd2020-11-24T22:05:29ZengPublishing House ZaslavskyMìžnarodnij Endokrinologìčnij Žurnal2224-07212307-14272016-05-01124.76334010.22141/2224-0721.4.76.2016.7779677796Therapy of Primary Hypothyroidism with α-Lipoic Acid Review of Studies ResultsA.V. Savustyanenko0Publishing House «Zaslavsky», KyivPrimary hypothyroidism occurs in the general population with an incidence of 0.5–1 %, and includes congenital and acquired (due to autoimmune thyroiditis, after surgical removal of the thyroid gland or treatment with radioactive iodine) forms. The basic treatment of primary hypothyroidism is replacement therapy with L-thyroxine. Combined administration of L-thyroxine and α-lipoic acid resulted in more marked decrease of oxidative stress, hyperlipidemia, hyperactivity of the immune system, endothelial dysfunction and neurological disorders, observed in patients with primary hypothyroidism, as compared to monotherapy with L-thyroxine. α-lipoic acid use was effective in adults and children, in case of parenteral and/or oral administration.http://iej.zaslavsky.com.ua/article/view/77796primary hypothyroidismα-lipoic acid |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
A.V. Savustyanenko |
| spellingShingle |
A.V. Savustyanenko Therapy of Primary Hypothyroidism with α-Lipoic Acid Review of Studies Results Mìžnarodnij Endokrinologìčnij Žurnal primary hypothyroidism α-lipoic acid |
| author_facet |
A.V. Savustyanenko |
| author_sort |
A.V. Savustyanenko |
| title |
Therapy of Primary Hypothyroidism with α-Lipoic Acid Review of Studies Results |
| title_short |
Therapy of Primary Hypothyroidism with α-Lipoic Acid Review of Studies Results |
| title_full |
Therapy of Primary Hypothyroidism with α-Lipoic Acid Review of Studies Results |
| title_fullStr |
Therapy of Primary Hypothyroidism with α-Lipoic Acid Review of Studies Results |
| title_full_unstemmed |
Therapy of Primary Hypothyroidism with α-Lipoic Acid Review of Studies Results |
| title_sort |
therapy of primary hypothyroidism with α-lipoic acid review of studies results |
| publisher |
Publishing House Zaslavsky |
| series |
Mìžnarodnij Endokrinologìčnij Žurnal |
| issn |
2224-0721 2307-1427 |
| publishDate |
2016-05-01 |
| description |
Primary hypothyroidism occurs in the general population with an incidence of 0.5–1 %, and includes congenital and acquired (due to autoimmune thyroiditis, after surgical removal of the thyroid gland or treatment with radioactive iodine) forms. The basic treatment of primary hypothyroidism is replacement therapy with L-thyroxine. Combined administration of L-thyroxine and α-lipoic acid resulted in more marked decrease of oxidative stress, hyperlipidemia, hyperactivity of the immune system, endothelial dysfunction and neurological disorders, observed in patients with primary hypothyroidism, as compared to monotherapy with L-thyroxine. α-lipoic acid use was effective in adults and children, in case of parenteral and/or oral administration. |
| topic |
primary hypothyroidism α-lipoic acid |
| url |
http://iej.zaslavsky.com.ua/article/view/77796 |
| work_keys_str_mv |
AT avsavustyanenko therapyofprimaryhypothyroidismwithalipoicacidreviewofstudiesresults |
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