Diagnosis and management of inflammatory bowel disease-associated neoplasia: considerations in the modern era

Diagnosis and management of inflammatory bowel disease-associated neoplasia: considerations in the modern era

Patients with inflammatory bowel disease (IBD) are at an increased risk of developing intestinal neoplasia—particularly colorectal neoplasia, including dysplasia and colorectal cancer (CRC)—as a primary consequence of chronic inflammation. While the current incidence of CRC in IBD is lower compared...

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Main Authors: Jordan E. Axelrad, Shailja C. Shah
Format: Article
Language:English
Published: SAGE Publishing 2020-05-01
Series:Therapeutic Advances in Gastroenterology
Online Access:https://doi.org/10.1177/1756284820920779
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spelling doaj-29fc2ccb6a744386b2cf7e1ad3e2775e2020-11-25T03:36:02ZengSAGE PublishingTherapeutic Advances in Gastroenterology1756-28482020-05-011310.1177/1756284820920779Diagnosis and management of inflammatory bowel disease-associated neoplasia: considerations in the modern eraJordan E. AxelradShailja C. ShahPatients with inflammatory bowel disease (IBD) are at an increased risk of developing intestinal neoplasia—particularly colorectal neoplasia, including dysplasia and colorectal cancer (CRC)—as a primary consequence of chronic inflammation. While the current incidence of CRC in IBD is lower compared with prior decades, due, in large part, to more effective therapies and improved colonoscopic technologies, CRC still accounts for a significant proportion of IBD-related deaths. The focus of this review is on the pathogenesis; epidemiology, including disease- and patient-related risk factors; diagnosis; surveillance; and management of IBD-associated neoplasia.https://doi.org/10.1177/1756284820920779
collection DOAJ
language English
format Article
sources DOAJ
author Jordan E. Axelrad
Shailja C. Shah
spellingShingle Jordan E. Axelrad
Shailja C. Shah
Diagnosis and management of inflammatory bowel disease-associated neoplasia: considerations in the modern era
Therapeutic Advances in Gastroenterology
author_facet Jordan E. Axelrad
Shailja C. Shah
author_sort Jordan E. Axelrad
title Diagnosis and management of inflammatory bowel disease-associated neoplasia: considerations in the modern era
title_short Diagnosis and management of inflammatory bowel disease-associated neoplasia: considerations in the modern era
title_full Diagnosis and management of inflammatory bowel disease-associated neoplasia: considerations in the modern era
title_fullStr Diagnosis and management of inflammatory bowel disease-associated neoplasia: considerations in the modern era
title_full_unstemmed Diagnosis and management of inflammatory bowel disease-associated neoplasia: considerations in the modern era
title_sort diagnosis and management of inflammatory bowel disease-associated neoplasia: considerations in the modern era
publisher SAGE Publishing
series Therapeutic Advances in Gastroenterology
issn 1756-2848
publishDate 2020-05-01
description Patients with inflammatory bowel disease (IBD) are at an increased risk of developing intestinal neoplasia—particularly colorectal neoplasia, including dysplasia and colorectal cancer (CRC)—as a primary consequence of chronic inflammation. While the current incidence of CRC in IBD is lower compared with prior decades, due, in large part, to more effective therapies and improved colonoscopic technologies, CRC still accounts for a significant proportion of IBD-related deaths. The focus of this review is on the pathogenesis; epidemiology, including disease- and patient-related risk factors; diagnosis; surveillance; and management of IBD-associated neoplasia.
url https://doi.org/10.1177/1756284820920779
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AT shailjacshah diagnosisandmanagementofinflammatoryboweldiseaseassociatedneoplasiaconsiderationsinthemodernera
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