Analysis of Risk Factors for Development of Cognitive Disorders in Maintenance Hemodialysis Patients – Pilot Study
Prevalence of cognitive disorders is high in maintenance hemodialysis patients. Montreal cognitive assessment (MoCA) is used for detecting and evaluation of cognitive disorder degree in this patient population. In examined patient population, only 5 (12.5%) of them had normal cognitive function (MoC...
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Online Access: | https://doi.org/10.1515/sjecr-2016-0090 |
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doaj-2a04f03320ec42669e4d591af1d9a3ac2021-09-05T14:00:39ZengSciendoSerbian Journal of Experimental and Clinical Research 1820-86652335-075X2017-12-0118433133510.1515/sjecr-2016-0090sjecr-2016-0090Analysis of Risk Factors for Development of Cognitive Disorders in Maintenance Hemodialysis Patients – Pilot StudyJovanovic Milena0Todorovic Zeljko1Milovanovic Dragan2Draskovic Branislava3Todorovic Andreja4Petrovic Dejan5Clinic for Urology, Nephrology and Dialysis, Center for Nephrology and Dialysis, Clinical center “Kragujevac”, Kragujevac, SerbiaFaculty of medical sciences Kragujevac, University of Kragujevac, Kragujevac, SerbiaFaculty of medical sciences Kragujevac, University of Kragujevac, Kragujevac, SerbiaClinic for Urology, Nephrology and Dialysis, Center for Nephrology and Dialysis, Clinical center “Kragujevac”, Kragujevac, SerbiaDepartment of Cardiology, General Hospital of Cuprija, Cuprija, SerbiaClinic for Urology, Nephrology and Dialysis, Center for Nephrology and Dialysis, Clinical center “Kragujevac”, Kragujevac, SerbiaPrevalence of cognitive disorders is high in maintenance hemodialysis patients. Montreal cognitive assessment (MoCA) is used for detecting and evaluation of cognitive disorder degree in this patient population. In examined patient population, only 5 (12.5%) of them had normal cognitive function (MoCA ≥26). Mild cognitive impairment (MoCA 18-26) was found in 65.9% (29) patients, while moderate cognitive disorder (MoCA 10-17) was detected in 6 (21.6%) patients. Major cognitive disorder wasn’t detected in examined population. Statistically significant correlation was not established between laboratory parameters and overall MoCA score. Statistically significant correlation, however, was established between MoCA item that evaluates space and time orientation and intermediate secondary hyperparathyroidism and space and time orientation and severe secondary hyperparathyroidism. Hemodynamic instability during hemodialysis and silent ischemia of the brain are increasing risk of appearance of cognitive disorders in maintenance hemodialysis patients.https://doi.org/10.1515/sjecr-2016-0090hemodialysiscognitionmocasecondary hyperparathyroidism |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Jovanovic Milena Todorovic Zeljko Milovanovic Dragan Draskovic Branislava Todorovic Andreja Petrovic Dejan |
spellingShingle |
Jovanovic Milena Todorovic Zeljko Milovanovic Dragan Draskovic Branislava Todorovic Andreja Petrovic Dejan Analysis of Risk Factors for Development of Cognitive Disorders in Maintenance Hemodialysis Patients – Pilot Study Serbian Journal of Experimental and Clinical Research hemodialysis cognition moca secondary hyperparathyroidism |
author_facet |
Jovanovic Milena Todorovic Zeljko Milovanovic Dragan Draskovic Branislava Todorovic Andreja Petrovic Dejan |
author_sort |
Jovanovic Milena |
title |
Analysis of Risk Factors for Development of Cognitive Disorders in Maintenance Hemodialysis Patients – Pilot Study |
title_short |
Analysis of Risk Factors for Development of Cognitive Disorders in Maintenance Hemodialysis Patients – Pilot Study |
title_full |
Analysis of Risk Factors for Development of Cognitive Disorders in Maintenance Hemodialysis Patients – Pilot Study |
title_fullStr |
Analysis of Risk Factors for Development of Cognitive Disorders in Maintenance Hemodialysis Patients – Pilot Study |
title_full_unstemmed |
Analysis of Risk Factors for Development of Cognitive Disorders in Maintenance Hemodialysis Patients – Pilot Study |
title_sort |
analysis of risk factors for development of cognitive disorders in maintenance hemodialysis patients – pilot study |
publisher |
Sciendo |
series |
Serbian Journal of Experimental and Clinical Research |
issn |
1820-8665 2335-075X |
publishDate |
2017-12-01 |
description |
Prevalence of cognitive disorders is high in maintenance hemodialysis patients. Montreal cognitive assessment (MoCA) is used for detecting and evaluation of cognitive disorder degree in this patient population. In examined patient population, only 5 (12.5%) of them had normal cognitive function (MoCA ≥26). Mild cognitive impairment (MoCA 18-26) was found in 65.9% (29) patients, while moderate cognitive disorder (MoCA 10-17) was detected in 6 (21.6%) patients. Major cognitive disorder wasn’t detected in examined population. Statistically significant correlation was not established between laboratory parameters and overall MoCA score. Statistically significant correlation, however, was established between MoCA item that evaluates space and time orientation and intermediate secondary hyperparathyroidism and space and time orientation and severe secondary hyperparathyroidism. Hemodynamic instability during hemodialysis and silent ischemia of the brain are increasing risk of appearance of cognitive disorders in maintenance hemodialysis patients. |
topic |
hemodialysis cognition moca secondary hyperparathyroidism |
url |
https://doi.org/10.1515/sjecr-2016-0090 |
work_keys_str_mv |
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