Korelasi antara Modification of Diet in Renal Disease (MDRD) dan Cystatin C Serum pada Usia 40–70 Tahun

Korelasi antara Modification of Diet in Renal Disease (MDRD) dan Cystatin C Serum pada Usia 40–70 Tahun

Reporting of the estimated glomerular filtration rate (GFR) in every creatinine test is suggested, despite the fact that every laboratory reports it in their result. Modification of Diet in Renal Disease (MDRD) is a formula that is used to estimate the GFR using serum creatinine. Serum cystatin C is...

Full description

Bibliographic Details
Main Authors: Jason Jus, Ronald Irwanto, Pusparini
Format: Article
Language:English
Published: Universitas Padjajaran 2016-09-01
Series:Majalah Kedokteran Bandung
Subjects:
Cystatin C
creatinine
eGFR
MDRD
Online Access:http://journal.fk.unpad.ac.id/index.php/mkb/article/view/605/pdf
id doaj-2a3d21a8b144455e97ea2c542bc6fe3f
record_format Article
spelling doaj-2a3d21a8b144455e97ea2c542bc6fe3f2020-11-24T21:11:56ZengUniversitas PadjajaranMajalah Kedokteran Bandung0126-074X2338-62232016-09-0148312913410.15395/mkb.v48n3.605Korelasi antara Modification of Diet in Renal Disease (MDRD) dan Cystatin C Serum pada Usia 40–70 TahunJason Jus0Ronald Irwanto1Pusparini2Fakultas Kedokteran Universitas Trisakti, Jakarta,Bagian Ilmu Penyakit Dalam Fakultas Kedokteran Universitas Trisakti, JakartaBagian Patologi Klinik Fakultas Kedokteran Universitas Trisakti, JakartaReporting of the estimated glomerular filtration rate (GFR) in every creatinine test is suggested, despite the fact that every laboratory reports it in their result. Modification of Diet in Renal Disease (MDRD) is a formula that is used to estimate the GFR using serum creatinine. Serum cystatin C is a relatively new test and superior for assessing kidney functions. The purpose of this study was to show the correlation between MDRD and serum cystatin C. A cross-sectional study was conducted using secondary data from 260 subjects, aged 40–70 years old to assess serum creatinine and serum cystatin C at a private laboratory in West Jakarta, during the period of January 2013–September 2014. The result of the study showed that the mean age of subjects was 55.7+7.8 years old, the mean serum cystatin C level was 0.99 + 0.6 mg/L, and the mean MDRD was 80.24±28.1 mL/min/1.73 m2. Pearson correlation analysis showed a negative correlation between MDRD and serum cystatin C with r = -0.767 and p =0.001. In conclusion, higher MDRD presents lower cystatin C serum; hence, MDRD can be used as an alternative renal function test when serum cystatin C is not available. [http://journal.fk.unpad.ac.id/index.php/mkb/article/view/605/pdfCystatin CcreatinineeGFRMDRD
collection DOAJ
language English
format Article
sources DOAJ
author Jason Jus
Ronald Irwanto
Pusparini
spellingShingle Jason Jus
Ronald Irwanto
Pusparini
Korelasi antara Modification of Diet in Renal Disease (MDRD) dan Cystatin C Serum pada Usia 40–70 Tahun
Majalah Kedokteran Bandung
Cystatin C
creatinine
eGFR
MDRD
author_facet Jason Jus
Ronald Irwanto
Pusparini
author_sort Jason Jus
title Korelasi antara Modification of Diet in Renal Disease (MDRD) dan Cystatin C Serum pada Usia 40–70 Tahun
title_short Korelasi antara Modification of Diet in Renal Disease (MDRD) dan Cystatin C Serum pada Usia 40–70 Tahun
title_full Korelasi antara Modification of Diet in Renal Disease (MDRD) dan Cystatin C Serum pada Usia 40–70 Tahun
title_fullStr Korelasi antara Modification of Diet in Renal Disease (MDRD) dan Cystatin C Serum pada Usia 40–70 Tahun
title_full_unstemmed Korelasi antara Modification of Diet in Renal Disease (MDRD) dan Cystatin C Serum pada Usia 40–70 Tahun
title_sort korelasi antara modification of diet in renal disease (mdrd) dan cystatin c serum pada usia 40–70 tahun
publisher Universitas Padjajaran
series Majalah Kedokteran Bandung
issn 0126-074X
2338-6223
publishDate 2016-09-01
description Reporting of the estimated glomerular filtration rate (GFR) in every creatinine test is suggested, despite the fact that every laboratory reports it in their result. Modification of Diet in Renal Disease (MDRD) is a formula that is used to estimate the GFR using serum creatinine. Serum cystatin C is a relatively new test and superior for assessing kidney functions. The purpose of this study was to show the correlation between MDRD and serum cystatin C. A cross-sectional study was conducted using secondary data from 260 subjects, aged 40–70 years old to assess serum creatinine and serum cystatin C at a private laboratory in West Jakarta, during the period of January 2013–September 2014. The result of the study showed that the mean age of subjects was 55.7+7.8 years old, the mean serum cystatin C level was 0.99 + 0.6 mg/L, and the mean MDRD was 80.24±28.1 mL/min/1.73 m2. Pearson correlation analysis showed a negative correlation between MDRD and serum cystatin C with r = -0.767 and p =0.001. In conclusion, higher MDRD presents lower cystatin C serum; hence, MDRD can be used as an alternative renal function test when serum cystatin C is not available. [
topic Cystatin C
creatinine
eGFR
MDRD
url http://journal.fk.unpad.ac.id/index.php/mkb/article/view/605/pdf
work_keys_str_mv AT jasonjus korelasiantaramodificationofdietinrenaldiseasemdrddancystatincserumpadausia4070tahun
AT ronaldirwanto korelasiantaramodificationofdietinrenaldiseasemdrddancystatincserumpadausia4070tahun
AT pusparini korelasiantaramodificationofdietinrenaldiseasemdrddancystatincserumpadausia4070tahun
_version_ 1716752122371899392

Similar Items