Muscular changes in animal models of heart failure with preserved ejection fraction: what comes closest to the patient?

Muscular changes in animal models of heart failure with preserved ejection fraction: what comes closest to the patient?

Abstract Aims Heart failure with preserved ejection fraction (HFpEF) is associated with reduced exercise capacity elicited by skeletal muscle (SM) alterations. Up to now, no clear medical treatment advice for HFpEF is available. Identification of the ideal animal model mimicking the human condition...

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Bibliographic Details
Main Authors: Keita Goto, Antje Schauer, Antje Augstein, Mei Methawasin, Henk Granzier, Martin Halle, Emeline M Van Craenenbroeck, Natale Rolim, Stephan Gielen, Burkert Pieske, Ephraim B. Winzer, Axel Linke, Volker Adams
Format: Article
Language:English
Published: Wiley 2021-02-01
Series:ESC Heart Failure
Subjects:
Skeletal muscle
Heart failure with preserved ejection fraction
Animal models
Online Access:https://doi.org/10.1002/ehf2.13142

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