Maternal obesity influences expression and DNA methylation of the adiponectin and leptin systems in human third-trimester placenta
Abstract Background It is well established that obesity is associated with dysregulation of the ratio between the two major adipokines leptin and adiponectin. Furthermore, it was recently reported that maternal obesity has a significant impact on placental development. Leptin and adiponectin are pre...
Main Authors: | Perrine Nogues, Esther Dos Santos, Hélène Jammes, Paul Berveiller, Lucie Arnould, François Vialard, Marie-Noëlle Dieudonné |
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Format: | Article |
Language: | English |
Published: |
BMC
2019-02-01
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Series: | Clinical Epigenetics |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s13148-019-0612-6 |
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