Extrarenal expression of α-klotho, the kidney related longevity gene, in Heterocephalus glaber, the long living Naked Mole Rat

Abstract The Naked Mole Rat (NMR), Heterocephalus glaber, provides an interesting model for studying biomarkers of longevity due to its long lifespan of more than 30 years, almost ten times longer than that of mice and rats. α-Klotho (klotho) is an aging-suppressor gene, and overexpression of klotho...

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Main Authors: M. Morevati, M. L. Mace, S. Egstrand, A. Nordholm, C. Doganli, J. Strand, J. L. Rukov, S. B. Torsetnes, V. Gorbunova, K. Olgaard, E. Lewin
Format: Article
Language:English
Published: Nature Publishing Group 2021-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-94972-1

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