Identification of a neo-epitope dominating endogenous CD8 T cell responses to MC-38 colorectal cancer
The murine MC-38 colorectal cancer model is a commonly used model for cancer with high mutational burden, which is sensitive for immune checkpoint immunotherapy. We set out to analyze endogenous CD8+ T cell responses to MC-38 neo-antigens in tumor-bearing mice and after anti-PD-L1 checkpoint therapy...
Main Authors: | Brett J. Hos, Marcel G.M. Camps, Jitske van den Bulk, Elena Tondini, Thomas C. van den Ende, Dina Ruano, Kees Franken, George M.C. Janssen, Arnoud Ru, Dmitri V. Filippov, Ramon Arens, Peter A. van Veelen, Noel Miranda, Ferry Ossendorp |
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Format: | Article |
Language: | English |
Published: |
Taylor & Francis Group
2020-01-01
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Series: | OncoImmunology |
Subjects: | |
Online Access: | http://dx.doi.org/10.1080/2162402X.2019.1673125 |
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