Seroprevalence, risk associations, and cost analysis of screening for viral infections among patients of cataract surgery
Purpose: The purpose of this study was to estimate the prevalence of blood-borne viral infections (triple H: HBV-hepatitis B virus, HCV-hepatitis C virus, and HIV-human immunodeficiency virus) among cataract patients, sought possible risk associations and discuss feasibility of universal preoperativ...
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doaj-2a5a2c5ff0964fe9a9df41451e20dbf92020-11-24T21:32:06ZengWolters Kluwer Medknow PublicationsIndian Journal of Ophthalmology0301-47381998-36892018-01-0166339439910.4103/ijo.IJO_726_17Seroprevalence, risk associations, and cost analysis of screening for viral infections among patients of cataract surgeryParveen RewriMadhavi SharmaD P VatsAparna SinghalPurpose: The purpose of this study was to estimate the prevalence of blood-borne viral infections (triple H: HBV-hepatitis B virus, HCV-hepatitis C virus, and HIV-human immunodeficiency virus) among cataract patients, sought possible risk associations and discuss feasibility of universal preoperative screening. Methods: This prospective, cross-sectional study enrolled consecutive patients of senile cataract. They were screened by immunoassay-based rapid diagnostic card tests for blood-borne viral infections. Positive cases were confirmed with confirmatory ELISA tests. Seropositive patients were enquired about the exposure to possible risk associations for acquiring these infections. Cost of card test per patient was calculated. Results: The prevalence of seropositivity for triple H viral infections (HBV, HCV, and HIV) among patients of senile cataract was 5.9% (95% confidence interval [CI]: 5.3–6.6), and HCV was most common viral infection. The dental extraction was most common (54%; 95% CI:48-60) possible risk association. The total cost of primary screening per patient for triple H infections(HBV, HCV, and HIV) was $0.93. Conclusion: The prevalence of blood-borne viral infection among cataract patients is high in this area. Awareness of the prevalence of blood-borne viral infections in service area, along with knowledge of rate of accidental exposure and risk of transmission would help to understand cost-effectiveness of universal preoperative screening before cataract surgery.http://www.ijo.in/article.asp?issn=0301-4738;year=2018;volume=66;issue=3;spage=394;epage=399;aulast=RewriCataractcost-analysishepatitis b virushepatitis c virushuman immunodeficiency virusprevalencescreening |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Parveen Rewri Madhavi Sharma D P Vats Aparna Singhal |
spellingShingle |
Parveen Rewri Madhavi Sharma D P Vats Aparna Singhal Seroprevalence, risk associations, and cost analysis of screening for viral infections among patients of cataract surgery Indian Journal of Ophthalmology Cataract cost-analysis hepatitis b virus hepatitis c virus human immunodeficiency virus prevalence screening |
author_facet |
Parveen Rewri Madhavi Sharma D P Vats Aparna Singhal |
author_sort |
Parveen Rewri |
title |
Seroprevalence, risk associations, and cost analysis of screening for viral infections among patients of cataract surgery |
title_short |
Seroprevalence, risk associations, and cost analysis of screening for viral infections among patients of cataract surgery |
title_full |
Seroprevalence, risk associations, and cost analysis of screening for viral infections among patients of cataract surgery |
title_fullStr |
Seroprevalence, risk associations, and cost analysis of screening for viral infections among patients of cataract surgery |
title_full_unstemmed |
Seroprevalence, risk associations, and cost analysis of screening for viral infections among patients of cataract surgery |
title_sort |
seroprevalence, risk associations, and cost analysis of screening for viral infections among patients of cataract surgery |
publisher |
Wolters Kluwer Medknow Publications |
series |
Indian Journal of Ophthalmology |
issn |
0301-4738 1998-3689 |
publishDate |
2018-01-01 |
description |
Purpose: The purpose of this study was to estimate the prevalence of blood-borne viral infections (triple H: HBV-hepatitis B virus, HCV-hepatitis C virus, and HIV-human immunodeficiency virus) among cataract patients, sought possible risk associations and discuss feasibility of universal preoperative screening. Methods: This prospective, cross-sectional study enrolled consecutive patients of senile cataract. They were screened by immunoassay-based rapid diagnostic card tests for blood-borne viral infections. Positive cases were confirmed with confirmatory ELISA tests. Seropositive patients were enquired about the exposure to possible risk associations for acquiring these infections. Cost of card test per patient was calculated. Results: The prevalence of seropositivity for triple H viral infections (HBV, HCV, and HIV) among patients of senile cataract was 5.9% (95% confidence interval [CI]: 5.3–6.6), and HCV was most common viral infection. The dental extraction was most common (54%; 95% CI:48-60) possible risk association. The total cost of primary screening per patient for triple H infections(HBV, HCV, and HIV) was $0.93. Conclusion: The prevalence of blood-borne viral infection among cataract patients is high in this area. Awareness of the prevalence of blood-borne viral infections in service area, along with knowledge of rate of accidental exposure and risk of transmission would help to understand cost-effectiveness of universal preoperative screening before cataract surgery. |
topic |
Cataract cost-analysis hepatitis b virus hepatitis c virus human immunodeficiency virus prevalence screening |
url |
http://www.ijo.in/article.asp?issn=0301-4738;year=2018;volume=66;issue=3;spage=394;epage=399;aulast=Rewri |
work_keys_str_mv |
AT parveenrewri seroprevalenceriskassociationsandcostanalysisofscreeningforviralinfectionsamongpatientsofcataractsurgery AT madhavisharma seroprevalenceriskassociationsandcostanalysisofscreeningforviralinfectionsamongpatientsofcataractsurgery AT dpvats seroprevalenceriskassociationsandcostanalysisofscreeningforviralinfectionsamongpatientsofcataractsurgery AT aparnasinghal seroprevalenceriskassociationsandcostanalysisofscreeningforviralinfectionsamongpatientsofcataractsurgery |
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