Combination of Peroxisome Proliferator-Activated Receptor (PPAR) Alpha and Gamma Agonists Prevents Corneal Inflammation and Neovascularization in a Rat Alkali Burn Model

Combination of Peroxisome Proliferator-Activated Receptor (PPAR) Alpha and Gamma Agonists Prevents Corneal Inflammation and Neovascularization in a Rat Alkali Burn Model

Peroxisome proliferator-activated receptor alpha (PPARα) and gamma (PPARγ) agonists have anti-inflammatory and anti-neovascularization effects, but few reports have tested the combination of PPARα and PPARγ agonists. In this study, we investigated the therapeutic effects of ophthalmic solutions of a...

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Bibliographic Details
Main Authors: Yuji Nakano, Takeshi Arima, Yutaro Tobita, Masaaki Uchiyama, Akira Shimizu, Hiroshi Takahashi
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:International Journal of Molecular Sciences
Subjects:
PPARα
PPARγ
combination of PPARα and PPARγ
cornea
alkali burn injury
neovascularization
Online Access:https://www.mdpi.com/1422-0067/21/14/5093

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