The metastatic promoter DEPDC1B induces epithelial‐mesenchymal transition and promotes prostate cancer cell proliferation via Rac1‐PAK1 signaling

The metastatic promoter DEPDC1B induces epithelial‐mesenchymal transition and promotes prostate cancer cell proliferation via Rac1‐PAK1 signaling

Abstract Metastasis is the major cause of prostate cancer (PCa)‐related mortality. Epithelial‐mesenchymal transition (EMT) is a vital characteristic feature that empowers cancer cells to adapt and survive at the beginning of metastasis. Therefore, it is essential to identify the regulatory mechanism...

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Bibliographic Details
Main Authors: Zean Li, Qiong Wang, Shirong Peng, Kai Yao, Junxiu Chen, Yiran Tao, Ze Gao, Fen Wang, Hui Li, Wenli Cai, Yiming Lai, Kaiwen Li, Xu Chen, Hai Huang
Format: Article
Language:English
Published: Wiley 2020-10-01
Series:Clinical and Translational Medicine
Subjects:
DEPDC1B
EMT
prostate cancer
Rac1
Online Access:https://doi.org/10.1002/ctm2.191

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