Genome-wide associations for benign prostatic hyperplasia reveal a genetic correlation with serum levels of PSA
Elderly males are often affected by benign prostatic hyperplasia and associated lower urinary tract symptoms (BPH/LUTS), but their link to prostate cancer risk is not well defined. Here, a genome-wide association study of BPH/LUTS patients from Iceland and the UK found 23 significant variants at 14...
Main Authors: | Julius Gudmundsson, Jon K. Sigurdsson, Lilja Stefansdottir, Bjarni A. Agnarsson, Helgi J. Isaksson, Olafur A. Stefansson, Sigurjon A. Gudjonsson, Daniel F. Gudbjartsson, Gisli Masson, Michael L. Frigge, Simon N. Stacey, Patrick Sulem, Gisli H. Halldorsson, Vinicius Tragante, Hilma Holm, Gudmundur I. Eyjolfsson, Olof Sigurdardottir, Isleifur Olafsson, Thorvaldur Jonsson, Eirikur Jonsson, Rosa B. Barkardottir, Rafn Hilmarsson, Folkert W. Asselbergs, Gudmundur Geirsson, Unnur Thorsteinsdottir, Thorunn Rafnar, Gudmar Thorleifsson, Kari Stefansson |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2018-11-01
|
Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-018-06920-9 |
Similar Items
-
A method for detecting long non-coding RNAs with tiled RNA expression microarrays.
by: Sigrun Helga Lund, et al.
Published: (2014-01-01) -
Genome-wide association meta-analysis yields 20 loci associated with gallstone disease
by: Egil Ferkingstad, et al.
Published: (2018-11-01) -
Eighty-eight variants highlight the role of T cell regulation and airway remodeling in asthma pathogenesis
by: Thorunn A. Olafsdottir, et al.
Published: (2020-01-01) -
Genetic variants associated with platelet count are predictive of human disease and physiological markers
by: Evgenia Mikaelsdottir, et al.
Published: (2021-09-01) -
The Science-Based Pathways to Understanding False Confessions and Wrongful Convictions
by: Gisli H. Gudjonsson, et al.
Published: (2021-02-01)