Neuropathic Pain Causes Pyramidal Neuronal Hyperactivity in the Anterior Cingulate Cortex

Neuropathic Pain Causes Pyramidal Neuronal Hyperactivity in the Anterior Cingulate Cortex

The anterior cingulate cortex (ACC) is thought to be important for acute pain perception as well as the development of chronic pain after peripheral nerve injury. Nevertheless, how ACC neurons respond to sensory stimulation under chronic pain states is not well understood. Here, we used an in vivo t...

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Bibliographic Details
Main Authors: Ruohe Zhao, Hang Zhou, Lianyan Huang, Zhongcong Xie, Jing Wang, Wen-Biao Gan, Guang Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-04-01
Series:Frontiers in Cellular Neuroscience
Subjects:
anterior cingulate cortex (ACC)
acute pain
neuropathic pain
two-photon imaging
pyramidal neurons
Online Access:http://journal.frontiersin.org/article/10.3389/fncel.2018.00107/full

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