Engineering antigen-specific T cells from genetically modified human hematopoietic stem cells in immunodeficient mice.

Engineering antigen-specific T cells from genetically modified human hematopoietic stem cells in immunodeficient mice.

There is a desperate need for effective therapies to fight chronic viral infections. The immune response is normally fastidious at controlling the majority of viral infections and a therapeutic strategy aimed at reestablishing immune control represents a potentially powerful approach towards treatin...

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Bibliographic Details
Main Authors: Scott G Kitchen, Michael Bennett, Zoran Galić, Joanne Kim, Qing Xu, Alan Young, Alexis Lieberman, Aviva Joseph, Harris Goldstein, Hwee Ng, Otto Yang, Jerome A Zack
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-12-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2785433?pdf=render

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