Time-courses of plasma IL-6 and HMGB-1 reflect initial severity of clinical presentation but do not predict poor neurologic outcome following subarachnoid hemorrhage

Time-courses of plasma IL-6 and HMGB-1 reflect initial severity of clinical presentation but do not predict poor neurologic outcome following subarachnoid hemorrhage

Objective: Patients with aneurysmal subarachnoid hemorrhage (aSAH) experience high mortality and morbidity. Neuroinflammation causes brain damage expansion after aSAH. Due to the complexity of the inflammatory response multiple biomarkers are needed to evaluate its' progression. We studied infl...

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Bibliographic Details
Main Authors: Heikki Kiiski, Jaakko Långsjö, Jyrki Tenhunen, Marika Ala-Peijari, Heini Huhtala, Mari Hämäläinen, Eeva Moilanen, Juha Öhman, Jukka Peltola
Format: Article
Language:English
Published: Elsevier 2017-03-01
Series:eNeurologicalSci
Subjects:
Aneurysmal subarachnoid hemorrhage
Biomarkers
Neuroinflammation
Inflammatory response
Il-6
HMGB1
Online Access:http://www.sciencedirect.com/science/article/pii/S2405650216300429

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http://www.sciencedirect.com/science/article/pii/S2405650216300429

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