Lochmolins A–G, New Sesquiterpenoids from the Soft Coral <em>Sinularia</em><em> lochmodes</em>
Seven new sesquiterpenoids, lochmolins A–G (<strong>1</strong>–<strong>7</strong>), were isolated from a Taiwanese soft coral <em>Sinularia lochmodes</em>. The structures of these metabolites were elucidated by exten...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2012-07-01
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Series: | Marine Drugs |
Subjects: | |
Online Access: | http://www.mdpi.com/1660-3397/10/7/1572 |
Summary: | Seven new sesquiterpenoids, lochmolins A–G (<strong>1</strong>–<strong>7</strong>), were isolated from a Taiwanese soft coral <em>Sinularia lochmodes</em>. The structures of these metabolites were elucidated by extensive spectroscopic study. Compounds <strong>1</strong>–<strong>4</strong> were found to inhibit the accumulation of the LPS-induced pro-inflammatory COX-2 protein in RAW264.7 macrophage cells. |
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ISSN: | 1660-3397 |