In-depth study of DNA binding of Cys2His2 finger domains in testis zinc-finger protein.
Previously, we identified that both fingers 1 and 2 in the three Cys2His2 zinc-finger domains (TZD) of testis zinc-finger protein specifically bind to its cognate DNA; however, finger 3 is non-sequence-specific. To gain insights into the interaction mechanism, here we further investigated the DNA-bi...
Main Authors: | Chun-Chi Chou, Shu-Yi Wei, Yuan-Chao Lou, Chinpan Chen |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2017-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC5383199?pdf=render |
Similar Items
-
An effective approach for generating a three-Cys<sub>2</sub>His<sub>2 </sub>zinc-finger-DNA complex model by docking
by: Rajasekaran M, et al.
Published: (2010-06-01) -
Structure characterization and docking study of three-Cys2His2 zinc-finger protein in complex with DNA
by: Chun-Chi Chou, et al.
Published: (2010) -
Cys2/His2 Zinc-Finger Proteins in Transcriptional Regulation of Flower Development
by: Tianqi Lyu, et al.
Published: (2018-08-01) -
Structural and functional studies of a zinc finger DNA-binding domain
by: Dutnall, Robert Nicholas
Published: (1995) -
The Role of Cys2-His2 Zinc Finger Transcription Factors in Polyol Metabolism, Asexual Development and Fumonisin Biosynthesis in Fusarium verticillioides
by: Malapi-Wight, Martha Maria
Published: (2013)