Prevalence of Low Plasma Vitamin B1 in the Stroke Population Admitted to Acute Inpatient Rehabilitation
Objective: To determine the prevalence of vitamin B1 (VitB1) deficiency in the stroke population admitted to acute inpatient rehabilitation. Design: Retrospective cohort study. Setting: Acute inpatient rehabilitation facility at an academic medical center. Participants: 119 consecutive stroke patien...
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doaj-2b192f1b9a9e45aea2102aef4342b17e2020-11-25T02:28:54ZengMDPI AGNutrients2072-66432020-04-01121034103410.3390/nu12041034Prevalence of Low Plasma Vitamin B1 in the Stroke Population Admitted to Acute Inpatient RehabilitationReza Ehsanian0Sean Anderson1Byron Schneider2David Kennedy3Vartgez Mansourian4Department of Physical Medicine and Rehabilitation, Vanderbilt University, Nashville, TN 37212, USADepartment of Physical Medicine and Rehabilitation, Vanderbilt University, Nashville, TN 37212, USADepartment of Physical Medicine and Rehabilitation, Vanderbilt University, Nashville, TN 37212, USADepartment of Physical Medicine and Rehabilitation, Vanderbilt University, Nashville, TN 37212, USADepartment of Physical Medicine and Rehabilitation, Vanderbilt University, Nashville, TN 37212, USAObjective: To determine the prevalence of vitamin B1 (VitB1) deficiency in the stroke population admitted to acute inpatient rehabilitation. Design: Retrospective cohort study. Setting: Acute inpatient rehabilitation facility at an academic medical center. Participants: 119 consecutive stroke patients admitted to stroke service from 1 January 2018 to 31 December 2018. Interventions: Not applicable. Main Outcome Measures: Plasma VitB1 level. Results: There were 17 patients (14%; 95% CI 9–22%) with low VitB1 with a range of 2–3 nmol/L, an additional 58 (49%; CI 40–58%) patients had normal low VitB1 with a range of 4–9 nmol/L, twenty-five patients (21%; CI 15–29%) had normal high VitB1 with a range of 10–15 nmol/L, and nineteen patients (16%; CI 10–24%) had high VitB1 with a range of 16–43 nmol/L. Conclusions: In this cohort of patients admitted to the stroke service at an acute rehabilitation facility, there is evidence of thiamine deficiency. Moreover, the data suggest that there is inadequate acute intake of VitB1. Given the role of thiamine deficiency in neurologic function, further study of the role of thiamine optimization in the acute stroke rehabilitation population is warranted.https://www.mdpi.com/2072-6643/12/4/1034thiaminethiaminvitamin B1thiamine deficiencystroke rehabilitationacute rehabilitation humans |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Reza Ehsanian Sean Anderson Byron Schneider David Kennedy Vartgez Mansourian |
spellingShingle |
Reza Ehsanian Sean Anderson Byron Schneider David Kennedy Vartgez Mansourian Prevalence of Low Plasma Vitamin B1 in the Stroke Population Admitted to Acute Inpatient Rehabilitation Nutrients thiamine thiamin vitamin B1 thiamine deficiency stroke rehabilitation acute rehabilitation humans |
author_facet |
Reza Ehsanian Sean Anderson Byron Schneider David Kennedy Vartgez Mansourian |
author_sort |
Reza Ehsanian |
title |
Prevalence of Low Plasma Vitamin B1 in the Stroke Population Admitted to Acute Inpatient Rehabilitation |
title_short |
Prevalence of Low Plasma Vitamin B1 in the Stroke Population Admitted to Acute Inpatient Rehabilitation |
title_full |
Prevalence of Low Plasma Vitamin B1 in the Stroke Population Admitted to Acute Inpatient Rehabilitation |
title_fullStr |
Prevalence of Low Plasma Vitamin B1 in the Stroke Population Admitted to Acute Inpatient Rehabilitation |
title_full_unstemmed |
Prevalence of Low Plasma Vitamin B1 in the Stroke Population Admitted to Acute Inpatient Rehabilitation |
title_sort |
prevalence of low plasma vitamin b1 in the stroke population admitted to acute inpatient rehabilitation |
publisher |
MDPI AG |
series |
Nutrients |
issn |
2072-6643 |
publishDate |
2020-04-01 |
description |
Objective: To determine the prevalence of vitamin B1 (VitB1) deficiency in the stroke population admitted to acute inpatient rehabilitation. Design: Retrospective cohort study. Setting: Acute inpatient rehabilitation facility at an academic medical center. Participants: 119 consecutive stroke patients admitted to stroke service from 1 January 2018 to 31 December 2018. Interventions: Not applicable. Main Outcome Measures: Plasma VitB1 level. Results: There were 17 patients (14%; 95% CI 9–22%) with low VitB1 with a range of 2–3 nmol/L, an additional 58 (49%; CI 40–58%) patients had normal low VitB1 with a range of 4–9 nmol/L, twenty-five patients (21%; CI 15–29%) had normal high VitB1 with a range of 10–15 nmol/L, and nineteen patients (16%; CI 10–24%) had high VitB1 with a range of 16–43 nmol/L. Conclusions: In this cohort of patients admitted to the stroke service at an acute rehabilitation facility, there is evidence of thiamine deficiency. Moreover, the data suggest that there is inadequate acute intake of VitB1. Given the role of thiamine deficiency in neurologic function, further study of the role of thiamine optimization in the acute stroke rehabilitation population is warranted. |
topic |
thiamine thiamin vitamin B1 thiamine deficiency stroke rehabilitation acute rehabilitation humans |
url |
https://www.mdpi.com/2072-6643/12/4/1034 |
work_keys_str_mv |
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