A novel therapy to attenuate acute kidney injury and ischemic allograft damage after allogenic kidney transplantation in mice.

A novel therapy to attenuate acute kidney injury and ischemic allograft damage after allogenic kidney transplantation in mice.

Ischemia followed by reperfusion contributes to the initial damage to allografts after kidney transplantation (ktx). In this study we tested the hypothesis that a tetrapeptide EA-230 (AQGV), might improve survival and attenuate loss of kidney function in a mouse model of renal ischemia/reperfusion i...

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Bibliographic Details
Main Authors: Faikah Gueler, Nelli Shushakova, Michael Mengel, Katja Hueper, Rongjun Chen, Xiaokun Liu, Joon-Keun Park, Hermann Haller, Gert Wensvoort, Song Rong
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4305280?pdf=render

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