Blood oxygenation changes resulting from suprathreshold transcranial magnetic stimulation
The hemodynamic response to low-intensity transcranial magnetic stimulation (TMS) has previously been demonstrated at motor cortex using near infrared spectroscopy (NIRS). To investigate the effect of TMS on oxy-hemoglobin (HbO) at prefrontal cortex, both subthreshold and suprathreshold TMS relative...
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doaj-2b2d6541ec3640d3b74ab1dbb403236f2021-03-18T04:35:02ZengElsevierBrain Stimulation1935-861X2011-07-0143165168Blood oxygenation changes resulting from suprathreshold transcranial magnetic stimulationRichard H. Thomson0Jerome J. Maller1Zafiris J. Daskalakis2Paul B. Fitzgerald3Monash Alfred Psychiatry Research Centre, The Alfred and Monash University School of Psychology and Psychiatry, Victoria, AustraliaMonash Alfred Psychiatry Research Centre, The Alfred and Monash University School of Psychology and Psychiatry, Victoria, AustraliaCentre for Addiction and Mental Health, University of Toronto, Toronto, Ontario, CanadaMonash Alfred Psychiatry Research Centre, The Alfred and Monash University School of Psychology and Psychiatry, Victoria, Australia; Correspondence: Professor Paul B. Fitzgerald, MAPRC, First Floor, Old Baker Building, The Alfred, Commercial Rd, Melbourne, Victoria, Australia, 3004.The hemodynamic response to low-intensity transcranial magnetic stimulation (TMS) has previously been demonstrated at motor cortex using near infrared spectroscopy (NIRS). To investigate the effect of TMS on oxy-hemoglobin (HbO) at prefrontal cortex, both subthreshold and suprathreshold TMS relative to resting motor threshold (rMT) were applied at typical intensities used in experimental settings. Although there was no significant change after 90% and 110% rMT TMS, there was a significant drop in HbO after 130% rMT TMS. This drop was maximal at approximately 8 seconds post-TMS. This study may have implications for determining appropriate TMS intensities when stimulating nonmotor areas.http://www.sciencedirect.com/science/article/pii/S1935861X10001622transcranial magnetic stimulationcortical blood flowoxygenated hemoglobinprefrontal cortexbrain stimulation |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Richard H. Thomson Jerome J. Maller Zafiris J. Daskalakis Paul B. Fitzgerald |
spellingShingle |
Richard H. Thomson Jerome J. Maller Zafiris J. Daskalakis Paul B. Fitzgerald Blood oxygenation changes resulting from suprathreshold transcranial magnetic stimulation Brain Stimulation transcranial magnetic stimulation cortical blood flow oxygenated hemoglobin prefrontal cortex brain stimulation |
author_facet |
Richard H. Thomson Jerome J. Maller Zafiris J. Daskalakis Paul B. Fitzgerald |
author_sort |
Richard H. Thomson |
title |
Blood oxygenation changes resulting from suprathreshold transcranial magnetic stimulation |
title_short |
Blood oxygenation changes resulting from suprathreshold transcranial magnetic stimulation |
title_full |
Blood oxygenation changes resulting from suprathreshold transcranial magnetic stimulation |
title_fullStr |
Blood oxygenation changes resulting from suprathreshold transcranial magnetic stimulation |
title_full_unstemmed |
Blood oxygenation changes resulting from suprathreshold transcranial magnetic stimulation |
title_sort |
blood oxygenation changes resulting from suprathreshold transcranial magnetic stimulation |
publisher |
Elsevier |
series |
Brain Stimulation |
issn |
1935-861X |
publishDate |
2011-07-01 |
description |
The hemodynamic response to low-intensity transcranial magnetic stimulation (TMS) has previously been demonstrated at motor cortex using near infrared spectroscopy (NIRS). To investigate the effect of TMS on oxy-hemoglobin (HbO) at prefrontal cortex, both subthreshold and suprathreshold TMS relative to resting motor threshold (rMT) were applied at typical intensities used in experimental settings. Although there was no significant change after 90% and 110% rMT TMS, there was a significant drop in HbO after 130% rMT TMS. This drop was maximal at approximately 8 seconds post-TMS. This study may have implications for determining appropriate TMS intensities when stimulating nonmotor areas. |
topic |
transcranial magnetic stimulation cortical blood flow oxygenated hemoglobin prefrontal cortex brain stimulation |
url |
http://www.sciencedirect.com/science/article/pii/S1935861X10001622 |
work_keys_str_mv |
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