T Cell Activation and Proinflammatory Cytokine Production in Clinically Cured Tuberculosis Are Time-Dependent and Accompanied by Upregulation of IL-10.

T Cell Activation and Proinflammatory Cytokine Production in Clinically Cured Tuberculosis Are Time-Dependent and Accompanied by Upregulation of IL-10.

Th1 cytokines are essential for the control of M. tuberculosis infection. The role of IL-10 in tuberculosis is controversial and there is an increasing body of evidence suggesting that the relationship between Th1 cytokines and IL-10 is not as antagonistic as it was first believed, and that these cy...

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Main Authors: Marcos Vinícius da Silva, Amanda A Figueiredo, Juliana R Machado, Lúcio C Castellano, Patricia B D Alexandre, Rafael F Oliveira, Gladstone E L Faria, Sanívia A L Pereira, Denise B R Rodrigues, Virmondes Rodrigues
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3688829?pdf=render

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