Preparation and Characterization of a Novel Swellable and Floating Gastroretentive Drug Delivery System (<i>sf</i>GRDDS) for Enhanced Oral Bioavailability of Nilotinib

Preparation and Characterization of a Novel Swellable and Floating Gastroretentive Drug Delivery System (<i>sf</i>GRDDS) for Enhanced Oral Bioavailability of Nilotinib

Regarding compliance and minimization of side effects of nilotinib therapy, there is a medical need to have a gastroretentive drug delivery system (GRDDS) to enhance the oral bioavailability that is able to administer an optimal dose in a quaque die (QD) or daily manner. In this study, the influence...

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Bibliographic Details
Main Authors: Hong-Liang Lin, Ling-Chun Chen, Wen-Ting Cheng, Wei-Jie Cheng, Hsiu-O Ho, Ming-Thau Sheu
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Pharmaceutics
Subjects:
gastroretentive drug delivery system
grdds
nilotinib
swelling and floating
kollidone sr
oral bioavailability
Online Access:https://www.mdpi.com/1999-4923/12/2/137

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