Targeting a cell surface vitamin D receptor on tumor-associated macrophages in triple-negative breast cancer
Triple-negative breast cancer (TNBC) is an aggressive tumor with limited treatment options and poor prognosis. We applied the in vivo phage display technology to isolate peptides homing to the immunosuppressive cellular microenvironment of TNBC as a strategy for non-malignant target discovery. We id...
Main Authors: | Fernanda I Staquicini, Amin Hajitou, Wouter HP Driessen, Bettina Proneth, Marina Cardó-Vila, Daniela I Staquicini, Christopher Markosian, Maria Hoh, Mauro Cortez, Anupama Hooda-Nehra, Mohammed Jaloudi, Israel T Silva, Jaqueline Buttura, Diana N Nunes, Emmanuel Dias-Neto, Bedrich Eckhardt, Javier Ruiz-Ramírez, Prashant Dogra, Zhihui Wang, Vittorio Cristini, Martin Trepel, Robin Anderson, Richard L Sidman, Juri G Gelovani, Massimo Cristofanilli, Gabriel N Hortobagyi, Zaver M Bhujwalla, Stephen K Burley, Wadih Arap, Renata Pasqualini |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2021-06-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/65145 |
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