When the Metal Makes the Difference: Template Syntheses of Tridentate and Tetradentate Salen-Type Schiff Base Ligands and Related Complexes
The reaction of organic molecules mediated by a metal center (<i>template synthesis</i>) can result in a final connectivity that may differ from the one obtained in the absence of the metal. The condensation of carbonyl fragments with primary amines form C=N iminic bonds, the so-called S...
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doaj-2ba03b5aefbb47de99e7068eed5568e42021-04-26T23:01:36ZengMDPI AGCrystals2073-43522021-04-011148348310.3390/cryst11050483When the Metal Makes the Difference: Template Syntheses of Tridentate and Tetradentate Salen-Type Schiff Base Ligands and Related ComplexesRita Mazzoni0Fabrizio Roncaglia1Luca Rigamonti2Dipartimento di Chimica Industriale ‘Toso Montanari’, Università degli Studi di Bologna, Viale del Risorgimento 4, 40136 Bologna, ItalyDipartimento di Scienze Chimiche e Geologiche, Università degli Studi di Modena e Reggio Emilia, via G. Campi 103, 41125 Modena, ItalyDipartimento di Scienze Chimiche e Geologiche, Università degli Studi di Modena e Reggio Emilia, via G. Campi 103, 41125 Modena, ItalyThe reaction of organic molecules mediated by a metal center (<i>template synthesis</i>) can result in a final connectivity that may differ from the one obtained in the absence of the metal. The condensation of carbonyl fragments with primary amines form C=N iminic bonds, the so-called Schiff bases, which can act as ligands for the templating metal center by means of the lone pair on the nitrogen atom. This review focuses on the template methods for the reaction between a carbonyl compound (mainly salicylaldehyde) and a primary aliphatic diamine able to prevent the double condensation on both amine groups and obtain tridentate N<sub>2</sub>O ligands. These adducts, still having one free amino group, can further react, yielding tetradentate salen-type Schiff base ligands. A screening over the transition metals able to show such a <i>template effect</i> will be presented, with particular attention to copper(II), together with their peculiar reactivity and the available crystal structure of the metal complexes and related coordination geometries.https://www.mdpi.com/2073-4352/11/5/483template effectSchiff base ligandsmetal coordinationimine formationoligonuclear complexesaliphatic diamine |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Rita Mazzoni Fabrizio Roncaglia Luca Rigamonti |
spellingShingle |
Rita Mazzoni Fabrizio Roncaglia Luca Rigamonti When the Metal Makes the Difference: Template Syntheses of Tridentate and Tetradentate Salen-Type Schiff Base Ligands and Related Complexes Crystals template effect Schiff base ligands metal coordination imine formation oligonuclear complexes aliphatic diamine |
author_facet |
Rita Mazzoni Fabrizio Roncaglia Luca Rigamonti |
author_sort |
Rita Mazzoni |
title |
When the Metal Makes the Difference: Template Syntheses of Tridentate and Tetradentate Salen-Type Schiff Base Ligands and Related Complexes |
title_short |
When the Metal Makes the Difference: Template Syntheses of Tridentate and Tetradentate Salen-Type Schiff Base Ligands and Related Complexes |
title_full |
When the Metal Makes the Difference: Template Syntheses of Tridentate and Tetradentate Salen-Type Schiff Base Ligands and Related Complexes |
title_fullStr |
When the Metal Makes the Difference: Template Syntheses of Tridentate and Tetradentate Salen-Type Schiff Base Ligands and Related Complexes |
title_full_unstemmed |
When the Metal Makes the Difference: Template Syntheses of Tridentate and Tetradentate Salen-Type Schiff Base Ligands and Related Complexes |
title_sort |
when the metal makes the difference: template syntheses of tridentate and tetradentate salen-type schiff base ligands and related complexes |
publisher |
MDPI AG |
series |
Crystals |
issn |
2073-4352 |
publishDate |
2021-04-01 |
description |
The reaction of organic molecules mediated by a metal center (<i>template synthesis</i>) can result in a final connectivity that may differ from the one obtained in the absence of the metal. The condensation of carbonyl fragments with primary amines form C=N iminic bonds, the so-called Schiff bases, which can act as ligands for the templating metal center by means of the lone pair on the nitrogen atom. This review focuses on the template methods for the reaction between a carbonyl compound (mainly salicylaldehyde) and a primary aliphatic diamine able to prevent the double condensation on both amine groups and obtain tridentate N<sub>2</sub>O ligands. These adducts, still having one free amino group, can further react, yielding tetradentate salen-type Schiff base ligands. A screening over the transition metals able to show such a <i>template effect</i> will be presented, with particular attention to copper(II), together with their peculiar reactivity and the available crystal structure of the metal complexes and related coordination geometries. |
topic |
template effect Schiff base ligands metal coordination imine formation oligonuclear complexes aliphatic diamine |
url |
https://www.mdpi.com/2073-4352/11/5/483 |
work_keys_str_mv |
AT ritamazzoni whenthemetalmakesthedifferencetemplatesynthesesoftridentateandtetradentatesalentypeschiffbaseligandsandrelatedcomplexes AT fabrizioroncaglia whenthemetalmakesthedifferencetemplatesynthesesoftridentateandtetradentatesalentypeschiffbaseligandsandrelatedcomplexes AT lucarigamonti whenthemetalmakesthedifferencetemplatesynthesesoftridentateandtetradentatesalentypeschiffbaseligandsandrelatedcomplexes |
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