Stretch-induced nerve injury: a proposed technique for the study of nerve regeneration and evaluation of the influence of gabapentin on this model

Stretch-induced nerve injury: a proposed technique for the study of nerve regeneration and evaluation of the influence of gabapentin on this model

The rat models currently employed for studies of nerve regeneration present distinct disadvantages. We propose a new technique of stretch-induced nerve injury, used here to evaluate the influence of gabapentin (GBP) on nerve regeneration. Male Wistar rats (300 g; n=36) underwent surgery and exposure...

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Bibliographic Details
Main Authors: J.A. Machado, M.F. Ghizoni, J. Bertelli, Gabriel C. Teske, Guilherme C. Teske, D.F. Martins, L. Mazzardo-Martins, E. Cargnin-Ferreira, A.R.S. Santos, A.P. Piovezan
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2013-11-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Nerve regeneration
Median nerve
Motor activity
Rat model
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2013001100929&lng=en&tlng=en

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