Redox Status, Procoagulant Activity, and Metabolome of Fresh Frozen Plasma in Glucose 6-Phosphate Dehydrogenase Deficiency

Redox Status, Procoagulant Activity, and Metabolome of Fresh Frozen Plasma in Glucose 6-Phosphate Dehydrogenase Deficiency

ObjectiveTransfusion of fresh frozen plasma (FFP) helps in maintaining the coagulation parameters in patients with acquired multiple coagulation factor deficiencies and severe bleeding. However, along with coagulation factors and procoagulant extracellular vesicles (EVs), numerous bioactive and prob...

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Bibliographic Details
Main Authors: Vassilis L. Tzounakas, Federica Gevi, Hara T. Georgatzakou, Lello Zolla, Issidora S. Papassideri, Anastasios G. Kriebardis, Sara Rinalducci, Marianna H. Antonelou
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-02-01
Series:Frontiers in Medicine
Subjects:
transfusion medicine
fresh frozen plasma
G6PD− donors
donor variation
metabolomics
extracellular vesicles
Online Access:http://journal.frontiersin.org/article/10.3389/fmed.2018.00016/full

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