Analysis on the risk factors of bacterial meningitis complicated with subdural effusion

• Main Authors: Zhi JIANG, Li-ming YANG, Jie ZHANG, Ze-shu NING, Bo CHEN
• Format: Article
• Language: English
• Published: Tianjin Huanhu Hospital 2015-08-01
• Series: Chinese Journal of Contemporary Neurology and Neurosurgery
• Subjects: Meningitis, bacterial; Subdural effusion; Risk factors; Regression analysis; Children
• Online Access: http://www.cjcnn.org/index.php/cjcnn/article/view/1250

<p><strong>Objective</strong> To investigate the risk factors of bacterial meningitis complicated with subdural effusion.  <strong>Methods </strong> The clinical data of children with bacterial meningitis in our hospital were collected and analyzed retrospectively. Logistic regression analysis was used to investigate the risk factors for subdural effusion.  <strong>Results</strong> A total of 128 cases were divided into control group (N = 64) and subdural effusion group (N = 64). There was no significant difference on serum erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), and white blood cell (WBC) between 2 groups (<em>P</em> &gt; 0.05, for all). Compared with control group, cerebrospinal fluid (CSF) WBC (<em>Z</em> = 3.126,<em> P</em> = 0.003), CSF protein (<em>Z</em> = 4.928, <em>P</em> = 0.000) and serum procalcitonin (PCT; <em>Z</em> = 2.823, <em>P</em> = 0.007) in subdural effusion group were significantly higher, while CSF glucose (<em>t</em> = 2.166, <em>P</em> = 0.033) was significantly lower. After treatment, CSF WBC (<em>Z</em> = 2.467, <em>P</em> = 0.012) in subdural effusion group was still significantly higher than that of control group, and CSF glucose (<em>t</em> = 4.938, <em>P</em> = 0.000) was still significantly lower. Logistic regression analysis showed that WBC in CSF (<em>P</em> = 0.027), CSF protein (<em>P</em> = 0.002) and serum PCT (<em>P</em> = 0.014) were independent risk factors for bacterial meningitis complicated with subdural effusion. <strong> Conclusions</strong> CSF examination of children with bacterial meningitis reveals significant increase of CSF WBC, CSF protein and serum PCT, suggesting concurrent subdural effusion is easily occurred.</p><p> </p><p><strong>DOI: </strong>10.3969/j.issn.1672-6731.2015.08.012</p>