The 133-kDa N-terminal domain enables myosin 15 to maintain mechanotransducing stereocilia and is essential for hearing
The precise assembly of inner ear hair cell stereocilia into rows of increasing height is critical for mechanotransduction and the sense of hearing. Yet, how the lengths of actin-based stereocilia are regulated remains poorly understood. Mutations of the molecular motor myosin 15 stunt stereocilia g...
Main Authors: | Qing Fang, Artur A Indzhykulian, Mirna Mustapha, Gavin P Riordan, David F Dolan, Thomas B Friedman, Inna A Belyantseva, Gregory I Frolenkov, Sally A Camper, Jonathan E Bird |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2015-08-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/08627 |
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