New Cinchona Oximes Evaluated as Reactivators of Acetylcholinesterase and Butyrylcholinesterase Inhibited by Organophosphorus Compounds

New Cinchona Oximes Evaluated as Reactivators of Acetylcholinesterase and Butyrylcholinesterase Inhibited by Organophosphorus Compounds

For the last six decades, researchers have been focused on finding efficient reactivators of organophosphorus compound (OP)-inhibited acetylcholinesterase (AChE) and butyrylcholinesterase (BChE). In this study, we have focused our research on a new oxime scaffold based on the Cinchona structure sinc...

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Bibliographic Details
Main Authors: Maja Katalinić, Antonio Zandona, Alma Ramić, Tamara Zorbaz, Ines Primožič, Zrinka Kovarik
Format: Article
Language:English
Published: MDPI AG 2017-07-01
Series:Molecules
Subjects:
nerve agents
pesticides
alkaloids
cytotoxicity
reversible inhibition
Online Access:https://www.mdpi.com/1420-3049/22/7/1234

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