The crystal structure of (RS)-7-chloro-2-(2,5-dimethoxyphenyl)-2,3-dihydroquinazolin-4(1H)-one: two hydrogen bonds generate an elegant three-dimensional framework structure
In the title compound, C61H15ClN2O3, the heterocyclic ring adopts an envelope conformation, folded across the N...N line, with the 2,5-dimethoxyphenyl unit occupying a quasi-axial site. There are two N—H...O hydrogen bonds in the structure: one hydrogen bond links molecules related by a 41 screw axi...
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International Union of Crystallography
2019-06-01
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| Series: | Acta Crystallographica Section E: Crystallographic Communications |
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| Online Access: | http://scripts.iucr.org/cgi-bin/paper?S2056989019007023 |
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doaj-2bc0085e5e9d40fcb6b189facadc7aba2020-11-25T01:49:48ZengInternational Union of CrystallographyActa Crystallographica Section E: Crystallographic Communications2056-98902019-06-0175684384710.1107/S2056989019007023zl2756The crystal structure of (RS)-7-chloro-2-(2,5-dimethoxyphenyl)-2,3-dihydroquinazolin-4(1H)-one: two hydrogen bonds generate an elegant three-dimensional framework structureKereyagalahally H. Narasimhamurthy0Chandra1Belakavadi K. Sagar2Kanchugarakoppal S. Rangappa3Hemmige S. Yathirajan4Christopher Glidewell5Department of Studies in Organic Chemistry, University of Mysore, Manasagangotri, Mysuru-570 006, IndiaDepartment of Physics, National Institute of Engineering, Mysore-570 008, IndiaDepartment of Studies in Chemistry, University of Mysore, Manasagangotri, Mysuru-570 006, IndiaDepartment of Studies in Chemistry, University of Mysore, Manasagangotri, Mysuru-570 006, IndiaDepartment of Studies in Chemistry, University of Mysore, Manasagangotri, Mysuru-570 006, IndiaSchool of Chemistry, University of St Andrews, St Andrews, Fife KY16 9ST, UKIn the title compound, C61H15ClN2O3, the heterocyclic ring adopts an envelope conformation, folded across the N...N line, with the 2,5-dimethoxyphenyl unit occupying a quasi-axial site. There are two N—H...O hydrogen bonds in the structure: one hydrogen bond links molecules related by a 41 screw axis to form a C(6) chain, and the other links inversion-related pairs of molecules to form an R22(8) ring. The ring motif links all of the chains into a continuous three-dimensional framework structure. Comparisons are made with the structures of some related compounds.http://scripts.iucr.org/cgi-bin/paper?S2056989019007023heterocyclic compoundsreduced quinazolinonescrystal structuremolecular conformationhydrogen bondingsupramolecular assembly |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Kereyagalahally H. Narasimhamurthy Chandra Belakavadi K. Sagar Kanchugarakoppal S. Rangappa Hemmige S. Yathirajan Christopher Glidewell |
| spellingShingle |
Kereyagalahally H. Narasimhamurthy Chandra Belakavadi K. Sagar Kanchugarakoppal S. Rangappa Hemmige S. Yathirajan Christopher Glidewell The crystal structure of (RS)-7-chloro-2-(2,5-dimethoxyphenyl)-2,3-dihydroquinazolin-4(1H)-one: two hydrogen bonds generate an elegant three-dimensional framework structure Acta Crystallographica Section E: Crystallographic Communications heterocyclic compounds reduced quinazolinones crystal structure molecular conformation hydrogen bonding supramolecular assembly |
| author_facet |
Kereyagalahally H. Narasimhamurthy Chandra Belakavadi K. Sagar Kanchugarakoppal S. Rangappa Hemmige S. Yathirajan Christopher Glidewell |
| author_sort |
Kereyagalahally H. Narasimhamurthy |
| title |
The crystal structure of (RS)-7-chloro-2-(2,5-dimethoxyphenyl)-2,3-dihydroquinazolin-4(1H)-one: two hydrogen bonds generate an elegant three-dimensional framework structure |
| title_short |
The crystal structure of (RS)-7-chloro-2-(2,5-dimethoxyphenyl)-2,3-dihydroquinazolin-4(1H)-one: two hydrogen bonds generate an elegant three-dimensional framework structure |
| title_full |
The crystal structure of (RS)-7-chloro-2-(2,5-dimethoxyphenyl)-2,3-dihydroquinazolin-4(1H)-one: two hydrogen bonds generate an elegant three-dimensional framework structure |
| title_fullStr |
The crystal structure of (RS)-7-chloro-2-(2,5-dimethoxyphenyl)-2,3-dihydroquinazolin-4(1H)-one: two hydrogen bonds generate an elegant three-dimensional framework structure |
| title_full_unstemmed |
The crystal structure of (RS)-7-chloro-2-(2,5-dimethoxyphenyl)-2,3-dihydroquinazolin-4(1H)-one: two hydrogen bonds generate an elegant three-dimensional framework structure |
| title_sort |
crystal structure of (rs)-7-chloro-2-(2,5-dimethoxyphenyl)-2,3-dihydroquinazolin-4(1h)-one: two hydrogen bonds generate an elegant three-dimensional framework structure |
| publisher |
International Union of Crystallography |
| series |
Acta Crystallographica Section E: Crystallographic Communications |
| issn |
2056-9890 |
| publishDate |
2019-06-01 |
| description |
In the title compound, C61H15ClN2O3, the heterocyclic ring adopts an envelope conformation, folded across the N...N line, with the 2,5-dimethoxyphenyl unit occupying a quasi-axial site. There are two N—H...O hydrogen bonds in the structure: one hydrogen bond links molecules related by a 41 screw axis to form a C(6) chain, and the other links inversion-related pairs of molecules to form an R22(8) ring. The ring motif links all of the chains into a continuous three-dimensional framework structure. Comparisons are made with the structures of some related compounds. |
| topic |
heterocyclic compounds reduced quinazolinones crystal structure molecular conformation hydrogen bonding supramolecular assembly |
| url |
http://scripts.iucr.org/cgi-bin/paper?S2056989019007023 |
| work_keys_str_mv |
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