An update on autoimmune retinopathy
Autoimmune retinopathy (AIR) refers to a group of rare autoimmune retinal degenerative diseases presumably caused by cross-reactivity of serum autoantibodies against retinal antigens. The pathogenesis of AIR remains largely presumptive and there are a significant number of antiretinal antibodies tha...
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Wolters Kluwer Medknow Publications
2020-01-01
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doaj-2bc2e762c3df4f3b9ee0c4c1de2b87f72020-11-25T03:21:37ZengWolters Kluwer Medknow PublicationsIndian Journal of Ophthalmology0301-47381998-36892020-01-016891829183710.4103/ijo.IJO_786_20An update on autoimmune retinopathyParthopratim Dutta MajumderAlessandro MarcheseFrancesco PichiItika GargAniruddha AgarwalAutoimmune retinopathy (AIR) refers to a group of rare autoimmune retinal degenerative diseases presumably caused by cross-reactivity of serum autoantibodies against retinal antigens. The pathogenesis of AIR remains largely presumptive and there are a significant number of antiretinal antibodies that have been detected in association with AIR. The diagnosis of AIR is largely based on the demonstration of antiretinal antibodies in the serum along with suggestive clinical features and ancillary investigations. A high index of suspicion along with early diagnosis and treatment may play a critical role to lower the risk of irreversible immunological damage to the retinal cells in these patients. A multi-disciplinary approach for complete management and evaluation is helpful in such conditions. Various therapeutic options have been described for the treatment of AIR, though there is no consensus on standard treatment protocol.http://www.ijo.in/article.asp?issn=0301-4738;year=2020;volume=68;issue=9;spage=1829;epage=1837;aulast=Duttaautoimmune retinopathycancer-associated retinopathyenolasemelanoma-associated retinopathyrecoverin |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Parthopratim Dutta Majumder Alessandro Marchese Francesco Pichi Itika Garg Aniruddha Agarwal |
spellingShingle |
Parthopratim Dutta Majumder Alessandro Marchese Francesco Pichi Itika Garg Aniruddha Agarwal An update on autoimmune retinopathy Indian Journal of Ophthalmology autoimmune retinopathy cancer-associated retinopathy enolase melanoma-associated retinopathy recoverin |
author_facet |
Parthopratim Dutta Majumder Alessandro Marchese Francesco Pichi Itika Garg Aniruddha Agarwal |
author_sort |
Parthopratim Dutta Majumder |
title |
An update on autoimmune retinopathy |
title_short |
An update on autoimmune retinopathy |
title_full |
An update on autoimmune retinopathy |
title_fullStr |
An update on autoimmune retinopathy |
title_full_unstemmed |
An update on autoimmune retinopathy |
title_sort |
update on autoimmune retinopathy |
publisher |
Wolters Kluwer Medknow Publications |
series |
Indian Journal of Ophthalmology |
issn |
0301-4738 1998-3689 |
publishDate |
2020-01-01 |
description |
Autoimmune retinopathy (AIR) refers to a group of rare autoimmune retinal degenerative diseases presumably caused by cross-reactivity of serum autoantibodies against retinal antigens. The pathogenesis of AIR remains largely presumptive and there are a significant number of antiretinal antibodies that have been detected in association with AIR. The diagnosis of AIR is largely based on the demonstration of antiretinal antibodies in the serum along with suggestive clinical features and ancillary investigations. A high index of suspicion along with early diagnosis and treatment may play a critical role to lower the risk of irreversible immunological damage to the retinal cells in these patients. A multi-disciplinary approach for complete management and evaluation is helpful in such conditions. Various therapeutic options have been described for the treatment of AIR, though there is no consensus on standard treatment protocol. |
topic |
autoimmune retinopathy cancer-associated retinopathy enolase melanoma-associated retinopathy recoverin |
url |
http://www.ijo.in/article.asp?issn=0301-4738;year=2020;volume=68;issue=9;spage=1829;epage=1837;aulast=Dutta |
work_keys_str_mv |
AT parthopratimduttamajumder anupdateonautoimmuneretinopathy AT alessandromarchese anupdateonautoimmuneretinopathy AT francescopichi anupdateonautoimmuneretinopathy AT itikagarg anupdateonautoimmuneretinopathy AT aniruddhaagarwal anupdateonautoimmuneretinopathy AT parthopratimduttamajumder updateonautoimmuneretinopathy AT alessandromarchese updateonautoimmuneretinopathy AT francescopichi updateonautoimmuneretinopathy AT itikagarg updateonautoimmuneretinopathy AT aniruddhaagarwal updateonautoimmuneretinopathy |
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1724613618104795136 |