Identification and functional validation of the novel antimalarial resistance locus PF10_0355 in Plasmodium falciparum.

Identification and functional validation of the novel antimalarial resistance locus PF10_0355 in Plasmodium falciparum.

The Plasmodium falciparum parasite's ability to adapt to environmental pressures, such as the human immune system and antimalarial drugs, makes malaria an enduring burden to public health. Understanding the genetic basis of these adaptations is critical to intervening successfully against malar...

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Bibliographic Details
Main Authors: Daria Van Tyne, Daniel J Park, Stephen F Schaffner, Daniel E Neafsey, Elaine Angelino, Joseph F Cortese, Kayla G Barnes, David M Rosen, Amanda K Lukens, Rachel F Daniels, Danny A Milner, Charles A Johnson, Ilya Shlyakhter, Sharon R Grossman, Justin S Becker, Daniel Yamins, Elinor K Karlsson, Daouda Ndiaye, Ousmane Sarr, Souleymane Mboup, Christian Happi, Nicholas A Furlotte, Eleazar Eskin, Hyun Min Kang, Daniel L Hartl, Bruce W Birren, Roger C Wiegand, Eric S Lander, Dyann F Wirth, Sarah K Volkman, Pardis C Sabeti
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-04-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3080868?pdf=render

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