Risk of Hepatitis C Virus transmission Following Upper Gastrointestinal Endoscopy
Background: Hepatitis C virus infection (HCV) is a main health problem in our country. It is thought that the transmission of hepatitis C virus (HCV) through the endoscopic procedures is a rare event. The aim of this study was to evaluate the risk of conventional disinfection in the transmission of...
Main Authors: | , , , |
---|---|
Format: | Article |
Language: | fas |
Published: |
Lorestan University of Medical Science
2006-11-01
|
Series: | Yafteh |
Subjects: | |
Online Access: | http://yafte.lums.ac.ir/browse.php?a_code=A-10-1-319&slc_lang=en&sid=1 |
id |
doaj-2be826879fd54359a83cdd442cda39c0 |
---|---|
record_format |
Article |
spelling |
doaj-2be826879fd54359a83cdd442cda39c02020-11-24T21:51:09ZfasLorestan University of Medical ScienceYafteh1563-07732006-11-01834754Risk of Hepatitis C Virus transmission Following Upper Gastrointestinal Endoscopyeskandar Hajiani0seyed jalal Hashemi1abdolrahim Masjedi-zade2mostafa Cheraghi3 Background: Hepatitis C virus infection (HCV) is a main health problem in our country. It is thought that the transmission of hepatitis C virus (HCV) through the endoscopic procedures is a rare event. The aim of this study was to evaluate the risk of conventional disinfection in the transmission of HCV. Materials and methods: A prospective study, comprising 456 consecutive upper gastrointestinal endoscopies was carried out in our endoscopy centers by using conventional disinfection (exposure of the endoscope to 2% glutaraldehyde for 4 minutes),Without altering the routine procedures. Anti-HCV antibodies were tested for all patients and a questionnaire was fulfilled by the patients to obtain information regarding the risk factors for HCV infection. Six months and one year later anti-HCV antibodies were repeated and positive results were confirmed by the PCR method.Five hundred healthy blood donors were used for the control group. Results: Five patients (1.09%) were anti-HCV-antibody positive. Anti-HCV-antibody-positive patients confirmed in three patients by PCR method . Anti-HCV antibodies were found in 6 healthy blood donors (1.2%) of controls.Transfusion, non-intravenous (i.v.) drug abuse, dental procedures, were found to be independent risk factors of HCV-positive the patients and controls groupsNo significant differences were observed between the patients and controls groups regarding the frequency of anti-HCV antibodies (P = 0.74). Conclusion: HCV does not seem to transmit through the endoscopic procedures. Conventional disinfection of the endoscope and accessories is sufficient for prevention of HCV transmission.http://yafte.lums.ac.ir/browse.php?a_code=A-10-1-319&slc_lang=en&sid=1Hepatitis Endoscopy Gastrointestinal system Antibody |
collection |
DOAJ |
language |
fas |
format |
Article |
sources |
DOAJ |
author |
eskandar Hajiani seyed jalal Hashemi abdolrahim Masjedi-zade mostafa Cheraghi |
spellingShingle |
eskandar Hajiani seyed jalal Hashemi abdolrahim Masjedi-zade mostafa Cheraghi Risk of Hepatitis C Virus transmission Following Upper Gastrointestinal Endoscopy Yafteh Hepatitis Endoscopy Gastrointestinal system Antibody |
author_facet |
eskandar Hajiani seyed jalal Hashemi abdolrahim Masjedi-zade mostafa Cheraghi |
author_sort |
eskandar Hajiani |
title |
Risk of Hepatitis C Virus transmission Following Upper Gastrointestinal Endoscopy |
title_short |
Risk of Hepatitis C Virus transmission Following Upper Gastrointestinal Endoscopy |
title_full |
Risk of Hepatitis C Virus transmission Following Upper Gastrointestinal Endoscopy |
title_fullStr |
Risk of Hepatitis C Virus transmission Following Upper Gastrointestinal Endoscopy |
title_full_unstemmed |
Risk of Hepatitis C Virus transmission Following Upper Gastrointestinal Endoscopy |
title_sort |
risk of hepatitis c virus transmission following upper gastrointestinal endoscopy |
publisher |
Lorestan University of Medical Science |
series |
Yafteh |
issn |
1563-0773 |
publishDate |
2006-11-01 |
description |
Background: Hepatitis C virus infection (HCV) is a main health problem in our country. It is thought that the transmission of hepatitis C virus (HCV) through the endoscopic procedures is a rare event. The aim of this study was to evaluate the risk of conventional disinfection in the transmission of HCV.
Materials and methods: A prospective study, comprising 456 consecutive upper gastrointestinal endoscopies was carried out in our endoscopy centers by using conventional disinfection (exposure of the endoscope to 2% glutaraldehyde for 4 minutes),Without altering the routine procedures. Anti-HCV antibodies were tested for all patients and a questionnaire was fulfilled by the patients to obtain information regarding the risk factors for HCV infection. Six months and one year later anti-HCV antibodies were repeated and positive results were confirmed by the PCR method.Five hundred healthy blood donors were used for the control group.
Results: Five patients (1.09%) were anti-HCV-antibody positive. Anti-HCV-antibody-positive patients confirmed in three patients by PCR method . Anti-HCV antibodies were found in 6 healthy blood donors (1.2%) of controls.Transfusion, non-intravenous (i.v.) drug abuse, dental procedures, were found to be independent risk factors of HCV-positive the patients and controls groupsNo significant differences were observed between the patients and controls groups regarding the frequency of anti-HCV antibodies (P = 0.74).
Conclusion: HCV does not seem to transmit through the endoscopic procedures. Conventional disinfection of the endoscope and accessories is sufficient for prevention of HCV transmission. |
topic |
Hepatitis Endoscopy Gastrointestinal system Antibody |
url |
http://yafte.lums.ac.ir/browse.php?a_code=A-10-1-319&slc_lang=en&sid=1 |
work_keys_str_mv |
AT eskandarhajiani riskofhepatitiscvirustransmissionfollowinguppergastrointestinalendoscopy AT seyedjalalhashemi riskofhepatitiscvirustransmissionfollowinguppergastrointestinalendoscopy AT abdolrahimmasjedizade riskofhepatitiscvirustransmissionfollowinguppergastrointestinalendoscopy AT mostafacheraghi riskofhepatitiscvirustransmissionfollowinguppergastrointestinalendoscopy |
_version_ |
1725880130814869504 |