Latency reversal agents affect differently the latent reservoir present in distinct CD4+ T subpopulations.

Latency reversal agents affect differently the latent reservoir present in distinct CD4+ T subpopulations.

Latency reversal agents (LRAs) have proven to induce HIV-1 transcription in vivo but are ineffective at decreasing the size of the latent reservoir in antiretroviral treated patients. The capacity of the LRAs to perturb the viral reservoir present in distinct subpopulations of cells is currently unk...

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Bibliographic Details
Main Authors: Judith Grau-Expósito, Laura Luque-Ballesteros, Jordi Navarro, Adrian Curran, Joaquin Burgos, Esteban Ribera, Ariadna Torrella, Bibiana Planas, Rosa Badía, Mario Martin-Castillo, Jesús Fernández-Sojo, Meritxell Genescà, Vicenç Falcó, Maria J Buzon
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-08-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1007991

Internet

https://doi.org/10.1371/journal.ppat.1007991

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