Topical TRPM8 Agonist for Relieving Neuropathic Ocular Pain in Patients with Dry Eye: A Pilot Study
Background: Activation of TRPM8, a cold-sensing receptor located on the cornea and eyelid, has the potential to relieve the neuropathic ocular pain (NOP) in dry eye (DE) by inhibiting other aberrant nociceptive inputs. We aimed to investigate the effect of a topical TRPM8 agonist, cryosim-3 (C3), on...
Main Authors: | Hyeon Jeong Yoon, Jonghwa Kim, Jee Myung Yang, Edward T. Wei, Seong Jin Kim, Kyung Chul Yoon |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-01-01
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Series: | Journal of Clinical Medicine |
Subjects: | |
Online Access: | https://www.mdpi.com/2077-0383/10/2/250 |
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