The prognostic significance of topoisomerase II alpha protein in early stage luminal breast cancer

The prognostic significance of topoisomerase II alpha protein in early stage luminal breast cancer

Abstract Background Topoisomerase II alpha (TOP2A) protein has been shown to be a proliferation marker associated with tumor grade and Ki67 index. The prognostic effect of TOP2A seems different among different subtypes of breast cancer. The current study evaluated the prognostic impact of TOP2A prot...

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Bibliographic Details
Main Authors: Xin An, Fei Xu, Rongzhen Luo, Qiufan Zheng, Jiabin Lu, Yanhua Yang, Tao Qin, Zhongyu Yuan, Yanxia Shi, Wenqi Jiang, Shusen Wang
Format: Article
Language:English
Published: BMC 2018-03-01
Series:BMC Cancer
Subjects:
Luminal breast cancer
Late recurrence
Prognostic factor
Survival
Topoisomerase II alpha
Online Access:http://link.springer.com/article/10.1186/s12885-018-4170-7

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